THAI RESEARCHERS DISCOVER ANTI-CANCER FORMULA FROM MANGOSTEEN

Food and Healthcare Press Releases Wednesday August 8, 2012 16:33
Bangkok--8 Aug--Thai Mangosteen Research and Development Center

Thirty five years ago, a group of researchers at Prince of Songkhla University and Chiang Mai University successfully extracted an interesting substance from mangosteen peel. Called GM-1, the substance is found to be effective in killing bacteria that are antibiotic resistant, three times better cure of inflammation than aspirin, have better antioxidant quality than vitamin E and most importantly can effectively kill cancer cells in the lab. From such substance, the researchers produced antibacterial cream that provides better treatment of wound with Streptococci and Staphylococcus bacteria that are resistant to penicillin and methicillin. That was when mangosteen peels, which once created a lot of pollution and waste, become valuable.

In the peak of fruit season, mangosteen, like many other fruits, becomes abundant and thus the price is lower while waste increases. In 2009, a group of researcher at the Thai Mangosteen Research and Development Center, produced mangosteen juice that provides a good solution to people with imbalance immunity. The researchers controlled the GM-1 in the juice at the appropriate level in order to produce the best effect to health. Mangosteens then become even more interesting among scientists and researchers.

Now, new discovery of the purple skin fruits, which are known as the Queen of Thai fruits, has stunned the global medical industry. Asian Phytoceuticals Public Company Limited’s Thai Mangosteen Research and Development Center, in cooperation with Chiang Mai University have conducted a research further on GM-1 admixed formula at the Biomedical Technology Research Center, Chiang Mai University, and found that at controlled level, such natural extract from mangosteen effectively produce balancing immunity (BIM). At different levels, the natural extract produces different results. It is therefore very effective in treating patients with different problems related to imbalance immunity. In the experiment, it is found that volunteers who consumed 2 gm of BIM substance for 15 days, Th1 cells doubled while TH17 cells were increased by 5 times.

It is known for more than 20 years among immunologists that Th1, a type of white blood cells enable body immunity to effectively eliminate foreign cells, such a fungi, bacteria, virus and cancer cells. Th17 cells were discovered in 2007 and found to be highly effective in preventing cancer cells to grow and inhibiting cancer symptoms. The discovery that BIM can increase the number of the two white blood cells, especially Th17, is a real breakthrough.

Prof. Dr. Pichaet Wiriyachitra, head researcher, Thai Mangosteen Research and Development Center, commented on the discovery of BIM and its effectiveness in promotion Th17:

“We are so proud of Thai researchers for this valuable discovery. Starting from GM-1 discovery, our brilliant researchers mixed it with natural extracts from guava, black sesame, soybeans and Asiatic Pennywort. Thanks to their knowledge, more than 30-year experience and creativity, they successfully formulate BIM which is effective in achieving immunity balance without any side effect. We believe this will help enhance quality of life of cancer patients.”

In its commitment to research and development for quality of life of consumers, Asian Phytoceuticals PCL fully supports the test of BIM on cancer patients at Chiang Mai University’s Faculty of Medicine. The researchers tested the extracts on final stage lung cancer patients who do not anymore respond to chemotherapy, conducted under supervision of Prof. Sumitra Thongprasert, MD, as well as patients suffering from other kinds of cancers who do not respond to normal therapy in the US and Italy. The result is very positive. It effectively enhanced quality of life of the patients and significant prolonged the life expectancy of final stage cancer patients who do not respond to normal chemotherapy.

While there is not yet completely safe and efficient way to expand Th17 in huge volume enough to treat cancer patients, the fruit extracts discovered by the Thai researcher team emerged as an interesting solution. More importantly, the natural extracts are proven safe and effective and are produced at lower cost of production compared to other medicine imported from other countries.

Given the significant success on BIM, quality of life of cancer patients will be significantly improved. In addition, it is believed to create greater economic value and social contribution to Thailand while natural resources are utilized.

For more information about BIM and the mangosteen extract, please contact the Thai Mangosteen Research and Development Center at Tel. 0 2 646 4 800

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